The most popular undergraduate major at Southeast Missouri State University is General Studies followed by Speech Communication and Rhetoric and Industrial Technology/Technician. A list of all 67 available majors and annual graduates is presented below. Also of interest, median earnings for Southeast Missouri State University graduates by major.
| Agriculture | 2 |
Agriculture |
Graduates |
| Agribusiness/Agricultural Business Operations | 7 |
| Animal Sciences | 6 |
| Plant Sciences | 3 |
| Horticultural Science | 4 |
Computer and Information Sciences |
Graduates |
| Computer and Information Sciences | 11 |
Education |
Graduates |
| Special Education and Teaching | 19 |
| Elementary Education and Teaching | 82 |
| Junior High/Intermediate/Middle School Education and Teaching | 13 |
| Early Childhood Education and Teaching | 22 |
| Art Teacher Education | 10 |
| Business Teacher Education | 2 |
| English/Language Arts Teacher Education | 11 |
| Foreign Language Teacher Education | 6 |
| Family and Consumer Sciences/Home Economics Teacher Education | 6 |
| Technology Teacher Education/Industrial Arts Teacher Education | 3 |
| Mathematics Teacher Education | 4 |
| Music Teacher Education | 9 |
| Physical Education Teaching and Coaching | 18 |
| Science Teacher Education/General Science Teacher Education | 9 |
| Social Studies Teacher Education | 17 |
| Speech Teacher Education | 1 |
Engineering |
Graduates |
| Engineering Physics/Applied Physics | 4 |
| Engineering Technology | 12 |
Engineering Technology |
Graduates |
| Industrial Technology/Technician | 86 |
| Computer Technology/Computer Systems Technology | 6 |
Foreign Languages |
Graduates |
| German Language and Literature | 3 |
| French Language and Literature | 2 |
| Spanish Language and Literature | 9 |
Work and Family Studies |
Graduates |
| Family and Consumer Sciences/Human Sciences | 46 |
English and Literature |
Graduates |
| English Language and Literature | 20 |
Liberal Arts and Humanities |
Graduates |
| General Studies | 178 |
Biology |
Graduates |
| Biology/Biological Sciences | 72 |
Mathematics |
Graduates |
| Mathematics | 8 |
Natural Resources Conservation |
Graduates |
| Environmental Science | 6 |
General Studies |
Graduates |
| Historic Preservation and Conservation | 9 |
| International/Global Studies | 2 |
| Multi-/Interdisciplinary Studies, Other | 4 |
Recreation, Leisure and Fitness Studies |
Graduates |
| Parks, Recreation and Leisure Studies | 14 |
| Health and Physical Education/Fitness | 42 |
| Sport and Fitness Administration/Management | 22 |
Philosophy and Religious Studies |
Graduates |
| Philosophy | 3 |
Physical Sciences |
Graduates |
| Chemistry | 14 |
| Physics | 3 |
Psychology |
Graduates |
| Psychology | 51 |
Homeland Security, Law Enforcement, Firefighting |
Graduates |
| Corrections | 84 |
Human Services |
Graduates |
| Social Work | 32 |
Social Sciences |
Graduates |
| Anthropology | 13 |
| Economics | 6 |
| Political Science and Government | 20 |
Visual and Performing Arts |
Graduates |
| Visual and Performing Arts | 7 |
| Drama and Dramatics/Theatre Arts | 5 |
| Art/Art Studies | 18 |
| Music | 12 |
Health Professions |
Graduates |
| Communication Sciences and Disorders | 22 |
| Athletic Training/Trainer | 2 |
| Registered Nursing/Registered Nurse | 85 |
Business |
Graduates |
| Business Administration and Management | 76 |
| Accounting | 54 |
| Administrative Assistant and Secretarial Science | 2 |
| Finance | 28 |
| Hospitality Administration/Management | 16 |
| International Business/Trade/Commerce | 11 |
| Marketing/Marketing Management | 33 |
History |
Graduates |
| History | 9 |
Communication |
Graduates |
| Speech Communication and Rhetoric | 112 |
| Organizational Communication | 6 |
Primary data source, U.S. Department of Education https://nces.ed.gov/collegenavigator/?id=179557 IPEDS survey data for Southeast Missouri State University.